B6: Plasticity of the Calvin-Benson cycle in Arabidopsis in response to changing light and nitrogen availability over a diurnal cycle

Dr. Anika Küken

Institute for Biochemistry and Biology, University of Potsdam, Karl-Liebknecht-Str. 24-25, Haus 29, 14476 Potsdam-Golm

Webpage: https://www.uni-potsdam.de/en/ibb-bioinformatik/members/anika-kueken

Summary

Project B6 will study plasticity in photosynthetic metabolism including the Calvin-Benson cycle (CBC) to nitrogen availability and light intensity as two key resources. The CBC is a key process in photosynthetic carbon fixation and intimately connected to plant central metabolism, yet no comprehensive kinetic models of the CBC are available. Thus, the project will generate a large-scale kinetic model of photosynthetic metabolism in leaves and use accession-specific model simulations to study the genetic basis of plasticity in central photosynthetic metabolism.

Project-related publications

Tong, H., Küken, A., Razaghi-Moghadam, Z., Nikoloski, Z. (2021) Characterization of effects of genetic variants via genome-scale metabolic modelling. Cellular and Molecular Life Sciences. 78:5123-5138(invited review).

Küken, A., Gennermann, K., Nikoloski, Z. (2020) Characterization of maximal enzyme catalytic rates in central metabolism of Arabidopsis thaliana.The Plant Journal 103, 2168-2177.

Schwahn, K., Küken, A., Kliebenstein, D.J., Fernie, A.R., Nikoloski, Z. (2016) Observability of plant metabolic networks is reflected in the correlation of metabolic profiles.Plant Physiol. 172, 1324–1333