Prof. Dr. med. Dr. phil. Michael Rapp

2024

Spanagel, R., Bach, P., Banaschewski, T., et al. The ReCoDe addiction research consortium: Losing and regaining control over drug intake—Findings and future perspectives. Addiction Biology. 2024; 29(7):e13419. doi:10.1111/adb.13419

2023

Förstner, B. R., Tschorn, M., Reinoso-Schiller, N., Maričić, L. M., Roecher, E., Kalman, J. L., ... & Rapp, M. A. (2023). Mapping Research Domain Criteria using a transdiagnostic mini-RDoC assessment in mental disorders: a confirmatory factor analysis. European Archives of Psychiatry and Clinical Neuroscience, 273(3), 527-539.

2022

Böge, K., Karnouk, C., Hoell, A., Tschorn, M., Kamp-Becker, I., Padberg, F., Übleis, A., Hasan, A., Falkai, P., Salize, H.-J., & others. (2022). Effectiveness and cost-effectiveness for the treatment of depressive symptoms in refugees and asylum seekers: A multi-centred randomized controlled trial. The Lancet Regional Health-Europe, 19, 100413. https://doi.org/10.1016/j.lanepe.2022.100413

Deeken, F., & Rapp, M. (2022). Technology-based interventions as an approach to treating apathy in people with dementia. International Psychogeriatrics, 34(2), 95–96. https://doi.org/10.1017/s1041610222000035

Deeken, F., Sánchez, A., Rapp, M. A., Denkinger, M., Brefka, S., Spank, J., Bruns, C., von Arnim, C. A. F., Kuster, O. C., & Conz..., L. O. (2022). Outcomes of a Delirium Prevention Program in Older Persons After Elective Surgery. JAMA Surgery, 157(2), e216370. https://doi.org/10.1001/jamasurg.2021.6370

Garbusow, M., Ebrahimi, C., Riemerschmid, C., Daldrup, L., Rothkirch, M., Chen, K., Chen, H., Belanger, M. J., Hentschel, A., Smolka, M. N., Heinz, A., Pilhatsch, M., & Rapp, M. A. (2022). Pavlovian-to-Instrumental Transfer across Mental Disorders: A Review. Neuropsychobiology, 120. https://doi.org/10.1159/000525579

Heinzel, S., Schwefel, M., Sanchez, A., Heinen, D., Fehm, L., Henze, R., Teran, C., Kallies, G., Rapp, M. A., Fydrich, T., Strohle, A., & Heissel, A. (2022). Physical exercise training as preceding treatment to cognitive behavioral therapy in mild to moderate major depressive disorder: A randomized controlled trial. Journal of Affective Disorders, 319, 9098. https://doi.org/10.1016/j.jad.2022.09.024

Hoffmann, S., Tschorn, M., Michalski, N., Hoebel, J., Forstner, B. R., Rapp, M. A., & Spallek, J. (2022). Association of regional socioeconomic deprivation and rurality with global developmental delay in early childhood: Data from mandatory school entry examinations in Germany. Health & Place, 75, 102794. https://doi.org/10.1016/j.healthplace.2022.102794

Mueckstein, M., Heinzel, S., Granacher, U., Brahms, M., Rapp, M. A., & Stelzel, C. (2022). Modality-specific effects of mental fatigue in multitasking. Acta Psychologica, 230, 103766. https://doi.org/10.1016/j.actpsy.2022.103766

Tschorn, M., Schulze, S., Forstner, B. R., Holmberg, C., Spallek, J., Heinz, A., & Rapp, M. A. (2022). Predictors and prevalence of hazardous alcohol use in middle-late to late adulthood in Europe. Aging & Mental Health, 110. https://doi.org/10.1080/13607863.2022.2076208

2021

Chen, H., Mojtahedzadeh, N., Belanger, M. J., Nebe, S., Kuitunen-Paul, S., Sebold, M., Garbusow, M., Huys, Q. J. M., Heinz, A., Rapp, M. A., & Smolka, M. N. (2021). Model-Based and Model-Free Control Predicts Alcohol Consumption Developmental Trajectory in Young Adults: A 3-Year Prospective Study. Biological Psychiatry, 89(10), 980989. https://doi.org/10.1016/j.biopsych.2021.01.009

Eschweiler, G. W., Czornik, M., Herrmann, M. L., Knauer, Y. P., Forkavets, O., von Arnim, C. A. F., Denkinger, M., Kuster, O., Conzelmann, L., Metz, B. R., Maurer, C., Kentischer, F., Deeken, F., Sanchez, A., Wagner, S., Mennig, E., Thomas, C., & Rapp, M. A. (2021). Presurgical Screening Improves Risk Prediction for Delirium in Elective Surgery of Older Patients: The PAWEL RISK Study. Frontiers in Aging Neuroscience, 13, 679933. https://doi.org/10.3389/fnagi.2021.679933

Rezo, A., Brunnhuber, S., Gil, F. P., Fernandez, A. C. S., & Rapp, M. A. (2021). Integrative medicine for mental health (INTEGRAL)-An ongoing health service research project comparing psychiatric routine care and integrative psychiatry. European Journal of Integrative Medicine, 48, 102014.

Schumann, G., Tschorn, M., Heinz, A., & Rapp, M. (2021). Jenseits von IMAGEN: populationsneurowissenschaftliche Strategien für klinische und globale Kohorten in den STRATIFY-und GIGA-Konsortien. Der Nervenarzt, 92(3), 234–242.

Tschorn, M., Lorenz, R. C., O’Reilly, P. F., Reichenberg, A., Banaschewski, T., Bokde, A. L., ... & Rapp, M. A. (2021). Differential predictors for alcohol use in adolescents as a function of familial risk. Translational psychiatry, 11(1), 157.

2020

Boge, K., Karnouk, C., Hahn, E., Schneider, F., Habel, U., Banaschewski, T., Meyer-Lindenberg, A., Salize, H. J., Kamp-Becker, I., Padberg, F., Hasan, A., Falkai, P., Rapp, M. A., Plener, P. L., Stamm, T., Elnahrawy, N., Lieb, K., Heinz, A., & Bajbouj, M. (2020). Mental health in refugees and asylum seekers (MEHIRA): study design and methodology of a prospective multicentre randomized controlled trail investigating the effects of a stepped and collaborative care model. European Archives of Psychiatry and Clinical Neuroscience, 270(1), 95106. https://doi.org/10.1007/s00406-019-00991-5

Deeken, F., Banaschewski, T., Kluge, U., & Rapp, M. A. (2020). Risk and protective factors for alcohol use disorders across the lifespan. Current Addiction Reports, 7(3), 245–251. https://doi.org/10.1007/s40429-020-00313-z

Heissel, A., Pietrek, A., Schwefel, M., Abula, K., Wilbertz, G., Heinzel, S., & Rapp, M. (2020). STEP.De study -a multicentre cluster-randomised effectiveness trial of exercise therapy for patients with depressive symptoms in healthcare services: study protocol. BMJ Open, 10(4), Article 4. https://doi.org/10.1136/bmjopen-2019-036287

Houtenbos, S. P., Schraplau, A., Rapp, M. A., Wippert, P.-M., Völler, H., Bonaventura, K., & Mayer, F. (2020). Reliability And Validity Of A Mobile Setup For Metabolic Syndrome Diagnosis Using Point-of-care Analyzers: 3915 Board# 232 May 30 9: 00 AM-10: 30 AM. Medicine & Science in Sports & Exercise, 52(7S), 1078–1079.

Schad, D. J., Rapp, M. A., Garbusow, M., Nebe, S., Sebold, M., Obst, E., Sommer, C., Deserno, L., Rabovsky, M., Friedel, E., Romanczuk-Seiferth, N., Wittchen, H.-U., Zimmermann, U. S., Walter, H., Sterzer, P., Smolka, M. N., Schlagenhauf, F., Heinz, A., Dayan, P., & Huys, Q. J. M. (2020). Dissociating neural learning signals in human sign- and goal-trackers. Nature Human Behaviour, 4(2), 201214. https://doi.org/10.1038/s41562-019-0765-5

Zech, P., Schuch, F., Pérez-Chaparro, C., Kangas, M., Rapp, M., & Heissel, A. (2020). Exercise, comorbidities, and health-related quality of life in people living with HIV: The HIBES cohort study. International Journal of Environmental Research and Public Health, 17(14), 5138. https://doi.org/10.3390/ijerph17145138

2019

Schad, D. J., Rapp, M. A., Garbusow, M., Nebe, S., Sebold, M., Obst, E., ... & Romanczuk-Seiferth, N. (2019). Dissociating neural learning signals in human sign-and goal-trackers. Nature human behaviour, 1-14.

Deeken, F., Rezo, A., Hinz, M., Discher, R., & Rapp, M. A. (2019). Evaluation of Technology-Based Interventions for Informal Caregivers of Patients With Dementia—A Meta-Analysis of Randomized Controlled Trials. The American Journal of Geriatric Psychiatry, 27(4), 426-445.

Schad, D. J., Garbusow, M., Friedel, E., Sommer, C., Sebold, M., Hägele, C., ... & Rapp, M. A. (2019). Neural correlates of instrumental responding in the context of alcohol-related cues index disorder severity and relapse risk. European archives of psychiatry and clinical neuroscience, 269(3), 295-308.

Sánchez, A., Thomas, C., Deeken, F., Wagner, S., Klöppel, S., Kentischer, F., ... & Rapp, M. A.. (2019). Patient safety, cost-effectiveness, and quality of life: reduction of delirium risk and postoperative cognitive dysfunction after elective procedures in older adults—study protocol for a stepped-wedge cluster randomized trial (PAWEL Study). Trials, 20(1), 71.

Heissel, A., Pietrek, A., Rapp, M. A., Heinzel, S., & Williams, G. (2019). Perceived Health Care Climate of Older People Attending an Exercise Program: Validation of the German Short Version of the Health Care Climate Questionnaire. Journal of aging and physical activity, 1(aop), 1-11.

2018

Gellert, P., Häusler, A., Suhr, R., Gholami, M., Rapp, M., Kuhlmey, A., & Nordheim, J. (2018). Testing the stress-buffering hypothesis of social support in couples coping with early-stage dementia. PloS One, 13(1), e0189849. https://doi.org/10.1371/journal.pone.0189849

Schad, D. J., Garbusow, M., Friedel, E., Sommer, C., Sebold, M., Hägele, C., …Rapp, M. A. (2018). Neural correlates of instrumental responding in the context of alcohol-related cues index disorder severity and relapse risk. European Archives of Psychiatry and Clinical Neuroscience. https://doi.org/10.1007/s00406-017-0860-4

Deeken, F., Häusler, A., Nordheim, J., Rapp, M., Knoll, N., & Rieckmann, N. (2018). Psychometric properties of the Perceived Stress Scale in a sample of German dementia patients and their caregivers. International Psychogeriatrics, 30(1), 39–47. https://doi.org/10.1017/S1041610217001387

2017

Gruebner, O., A. Rapp, M., Adli, M., Kluge, U., Galea, S., & Heinz, A. (2017). Cities and Mental Health. Deutsches Ärzteblatt International, 114(8), 121–127. https://doi.org/10.3238/arztebl.2017.0121

Gutzmann, H., & Rapp, M. (2017). Systematik organisch-symptomatischer Störungen. In H. J. Möller, G. Laux, & H. P. Kapfhammer (Hrsg.), Psychiatrie, Psychosomatik, Psychotherapie (S. 1351–1364). Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-49295-6_57

Heinzel, S., Lorenz, R. C., Duong, Q.-L., Rapp, M. A., & Deserno, L. (2017). Prefrontal-parietal effective connectivity during working memory in older adults. Neurobiology of Aging, 57, 18–27. https://doi.org/10.1016/j.neurobiolaging.2017.05.005

Heinzel, S., Rapp, M. A., Fydrich, T., Ströhle, A., Terán, C., Kallies, G., … Heissel, A. (2018). Neurobiological mechanisms of exercise and psychotherapy in depression: The SPeED study-Rationale, design, and methodological issues. Clinical Trials (London, England), 15(1), 53–64. https://doi.org/10.1177/1740774517729161

Rapp, M. A., Tschorn, M., Sebold, M., Garbusow, M., Smolka, M., & Heinz, A. (2017). Multivariate Prädiktion von Trinkverhalten: Das Ganze ist weniger als die Summe seiner Teile. In Suchttherapie (Bd. 18, S. S-11-04-11). Georg Thieme Verlag KG. https://doi.org/10.1055/s-0037-1604546

Sebold, M., Nebe, S., Garbusow, M., Guggenmos, M., Schad, D. J., Beck, A., … Heinz, A. (2017). When Habits Are Dangerous: Alcohol Expectancies and Habitual Decision Making Predict Relapse in Alcohol Dependence. Biological Psychiatry, 82(11), 847–856. https://doi.org/10.1016/j.biopsych.2017.04.019

Stelzel, C., Schauenburg, G., Rapp, M. A., Heinzel, S., & Granacher, U. (2017). Age-Related Interference between the Selection of Input-Output Modality Mappings and Postural Control-a Pilot Study. Frontiers in Psychology, 8, 613. https://doi.org/10.3389/fpsyg.2017.00613

2016

Bauer, M., Banaschewski, T., Heinz, A., Kamp-Becker, I., Meyer-Lindenberg, A., Padberg, F.,. . . Wittchen, H. (2016). Das deutsche Forschungsnetz zu psychischen Erkrankungen. Der Nervenarzt, 87(9), 989–1010. https://doi.org/10.1007/s00115-016-0169-y 

Booker, A., Jacob, L. E. C., Rapp, M. A., Bohlken, J., & Kostev, K. (2016). Risk factors for dementia diagnosis in German primary care practices. International Psychogeriatrics, 28(07), 1059–1065. https://doi.org/10.1017/S1041610215002082 

Garbusow, M., Schad, D. J., Sebold, M., Friedel, E., Bernhardt, N., Koch, S. P.,. . . Heinz, A. (2016). Pavlovian-to-instrumental transfer effects in the nucleus accumbens relate to relapse in alcohol dependence. Addiction Biology, 21(3), 719–731. https://doi.org/10.1111/adb.12243 

Häusler, A., Sánchez, A., Gellert, P., Deeken, F., Rapp, M. A., & Nordheim, J. (2016). Perceived stress and quality of life in dementia patients and their caregiving spouses: Does dyadic coping matter? International Psychogeriatrics, 28(11), 1857–1866. https://doi.org/10.1017/S1041610216001046 

Heinz, A., Kluge, U., & Rapp, M. A. (2016). Heritability of living in deprived neighbourhoods. Translational Psychiatry, 6(11), e941. https://doi.org/10.1038/tp.2016.215 

Heinz, A., Voss, M., Lawrie, S. M., Mishara, A., Bauer, M., Gallinat, J.,. . . Galderisi, S. (2016). Shall we really say goodbye to first rank symptoms? European Psychiatry, 37, 8–13. https://doi.org/10.1016/j.eurpsy.2016.04.010 

Heinz, A., Beck, A., & Rapp, M. A. (2016). Alcohol as an Environmental Mortality Hazard. JAMA Psychiatry, 73(6), 549. https://doi.org/10.1001/jamapsychiatry.2016.0399 

Heinzel, S., Lorenz, R. C., Pelz, P., Heinz, A., Walter, H., Kathmann, N.,. . . Stelzel, C. (2016). Neural correlates of training and transfer effects in working memory in older adults. NeuroImage, 134, 236–249. https://doi.org/10.1016/j.neuroimage.2016.03.068 

Konrad, M., Bohlken, J., Rapp, M. A., & Kostev, K. (2016). Depression risk in patients with heart failure in primary care practices in Germany. International Psychogeriatrics, 28(11), 1889–1894. https://doi.org/10.1017/S1041610216000867 

Liu, S., Schad, D. J., Kuschpel, M. S., Rapp, M. A., Heinz, A., & Allen, P. (2016). Music and Video Gaming during Breaks: Influence on Habitual versus Goal-Directed Decision Making. PLOS ONE, 11(3), e0150165. https://doi.org/10.1371/journal.pone.0150165 

Sebold, M., Schad, D. J., Nebe, S., Garbusow, M., Jünger, E., Kroemer, N. B.,. . . Huys, Q. J. M. (2016). Don't Think, Just Feel the Music: Individuals with Strong Pavlovian-to-Instrumental Transfer Effects Rely Less on Model-based Reinforcement Learning. Journal of Cognitive Neuroscience, 28(7), 985–995. https://doi.org/10.1162/jocn_a_00945 

Ströhle, A., & Rapp, M. A. (2016). Prevention of Cognitive Decline: A Physical Exercise Perspective on Brain Health in the Long Run. Journal of the American Medical Directors Association, 17(5), 461–462. https://doi.org/10.1016/j.jamda.2016.02.030 

2015

Aichberger, M. C., Heredia Montesinos, A., Bromand, Z., Yesil, R., Temur-Erman, S., Rapp, M. A.,. . . Schouler-Ocak, M. (2015). Suicide attempt rates and intervention effects in women of Turkish origin in Berlin. European Psychiatry, 30(4), 480–485. https://doi.org/10.1016/j.eurpsy.2014.12.003 

Aichberger, M. C., Bromand, Z., Rapp, M. A., Yesil, R., Montesinos, A. H., Temur-Erman, S.,. . . Schouler-Ocak, M. (2015). Perceived ethnic discrimination, acculturation, and psychological distress in women of Turkish origin in Germany. Social Psychiatry and Psychiatric Epidemiology, 50(11), 1691–1700. https://doi.org/10.1007/s00127-015-1105-3 

Bohlken, J., Schulz, M., Rapp, M. A., & Bätzing-Feigenbaum, J. (2015). Pharmacotherapy of dementia in Germany: Results from a nationwide claims database. European Neuropsychopharmacology, 25(12), 2333–2338. https://doi.org/10.1016/j.euroneuro.2015.09.014 

Heinz, A., Charlet, K., & Rapp, M. A. (2015). Public mental health: A call to action. World Psychiatry, 14(1), 49–50. https://doi.org/10.1002/wps.20182 

Kuschpel, M. S., Liu, S., Schad, D. J., Heinzel, S., Heinz, A., & Rapp, M. A. (2015). Differential effects of wakeful rest, music and video game playing on working memory performance in the n-back task. Frontiers in Psychology, 6, 27. https://doi.org/10.3389/fpsyg.2015.01683 

Rapp, M. A., Kluge, U., Penka, S., Vardar, A., Aichberger, M. C., Mundt, A. P.,. . . Heinz, A. (2015). When local poverty is more important than your income: Mental health in minorities in inner cities. World Psychiatry, 14(2), 249–250. https://doi.org/10.1002/wps.20221 

Ströhle, A., Schmidt, D. K., Schultz, F., Fricke, N., Staden, T., Hellweg, R.,. . . Rieckmann, N. (2015). Drug and Exercise Treatment of Alzheimer Disease and Mild Cognitive Impairment: A Systematic Review and Meta-Analysis of Effects on Cognition in Randomized Controlled Trials. The American Journal of Geriatric Psychiatry, 23(12), 1234–1249. https://doi.org/10.1016/j.jagp.2015.07.007 

Treusch, Y., Majic, T., Page, J., Gutzmann, H., Heinz, A., & Rapp, M. A. (2015). Apathy in nursing home residents with dementia: Results from a cluster-randomized controlled trial. European Psychiatry, 30(2), 251–257. https://doi.org/10.1016/j.eurpsy.2014.02.004 

2014

Garbusow, M., Schad, D. J., Sommer, C., Jünger, E., Sebold, M., Friedel, E.,. . . Rapp, M. A. (2014). Pavlovian-to-Instrumental Transfer in Alcohol Dependence: A Pilot Study. Neuropsychobiology, 70(2), 111–121. https://doi.org/10.1159/000363507 

Häusler, A. (2014). Psychosoziale Therapie bei beginnender Demenz: Das DYADEM-Unterstützungsprogramm für Menschen mit Demenz und ihre Partner. Frankfurt am Main: Mabuse-Verl.

Heinzel, S., Riemer, T. G., Schulte, S., Onken, J., Heinz, A., & Rapp, M. A. (2014). Catechol-O-methyltransferase (COMT) Genotype Affects Age-Related Changes in Plasticity in Working Memory: A Pilot Study. BioMed Research International, 2014(3), 1–7. https://doi.org/10.1155/2014/414351 

Schad, D. J., Jünger, E., Sebold, M., Garbusow, M., Bernhardt, N., Javadi, A.-H.,. . . Huys, Q. J. M. (2014). Processing speed enhances model-based over model-free reinforcement learning in the presence of high working memory functioning. Frontiers in Psychology, 5(587), 518. https://doi.org/10.3389/fpsyg.2014.01450 

Schlagenhauf, F., Huys, Q. J., Deserno, L., Rapp, M. A., Beck, A., Heinze, H.-J.,. . . Heinz, A. (2014). Striatal dysfunction during reversal learning in unmedicated schizophrenia patients. NeuroImage, 89, 171–180. https://doi.org/10.1016/j.neuroimage.2013.11.034 

Zaytseva, Y., Korsakova, N., Gurovich, I. Y., Heinz, A., & Rapp, M. A. (2014). Luria revisited: Complex motor phenomena in first episode schizophrenia and schizophrenia spectrum disorders. Psychiatry Research, 220(1-2), 145–151. https://doi.org/10.1016/j.psychres.2014.08.009 

2013

Heinzel, S., Schulte, S., Onken, J., Duong, Q.-L., Riemer, T. G., Heinz, A.,. . . Rapp, M. A. (2013). Working memory training improvements and gains in non-trained cognitive tasks in young and older adults. Aging, Neuropsychology, and Cognition, 21(2), 146–173. https://doi.org/10.1080/13825585.2013.790338 

Majić, T., Gutzmann, H., Heinz, A., Lang, U. E., & Rapp, M. A. (2013). Animal-Assisted Therapy and Agitation and Depression in Nursing Home Residents with Dementia: A Matched Case–Control Trial. The American Journal of Geriatric Psychiatry, 21(11), 1052–1059. https://doi.org/10.1016/j.jagp.2013.03.004 

Rapp, M. A., Mell, T., Majic, T., Treusch, Y., Nordheim, J., Niemann-Mirmehdi, M.,. . . Heinz, A. (2013). Agitation in Nursing Home Residents With Dementia (VIDEANT Trial): Effects of a Cluster-Randomized, Controlled, Guideline Implementation Trial. Journal of the American Medical Directors Association, 14(9), 690–695. https://doi.org/10.1016/j.jamda.2013.05.017 

Schlagenhauf, F., Rapp, M. A., Huys, Q. J. M., Beck, A., Wüstenberg, T., Deserno, L.,. . . Heinz, A. (2013). Ventral striatal prediction error signaling is associated with dopamine synthesis capacity and fluid intelligence. Human Brain Mapping, 34(6), 1490–1499. https://doi.org/10.1002/hbm.22000 

2012

Bromand, Z., Temur-Erman, S., Yesil, R., Heredia Montesinos, A., Aichberger, M. C., Kleiber, D.,. . . Rapp, M. A. (2012). Mental health of Turkish women in Germany: Resilience and risk factors. European Psychiatry, 27, S17-S21. https://doi.org/10.1016/S0924-9338(12)75703-6 

2010

Krampe, R. T., Doumas, M., Lavrysen, A., & Rapp, M. A. (2010). The costs of taking it slowly: Fast and slow movement timing in older age. Psychology and Aging, 25(4), 980–990. https://doi.org/10.1037/a0020090 

2009

Rieckmann, N. (2009). Gene-Environment Interactions and Depression. JAMA, 302(17), 1859. https://doi.org/10.1001/jama.2009.1578 

2006

Rapp, M. A., Schnaider-Beeri, M., Grossman, H. T., Sano, M., Perl, D. P., Purohit, D. P.,. . . Haroutunian, V. (2006). Increased Hippocampal Plaques and Tangles in Patients With Alzheimer Disease With a Lifetime History of Major Depression. Archives of General Psychiatry, 63(2), 161. https://doi.org/10.1001/archpsyc.63.2.161