Biohybrid Materials
Our research is located at the interface between chemistry and biology. We address various aspects related to the synthesis, the characterization, and the application of peptide/protein-polymer conjugates. Our topics have two main foci: biomedical research and bioeconomy. Typical research work includes synthesis, assembly and characterization of polymers, protein-polymer hybrid materials, solid-phase peptide synthesis, and enzyme-mediated ligations.
Our research interests include:
- Synthesis and characterization of protein- and peptide-polymer conjugates
- Enzyme-mediated site-specific functionalization of proteins
- Investigation of structure and structure–property relationships in protein-polymer conjugates
- Synthesis of biocompatible polymers for the stabilization of therapeutic proteins
- Nanobody-polymer conjugates as virus inhibitors
- Stimuli-responsive polymers to tune enzyme activities, peptide functionality and for targeted drug delivery
- Oriented and site-specific immobilization of proteins and peptides
- Formation of ultrathin protein-polymer membranes by interfacial self-assembly